Opportunity Information: Apply for CDC RFA CK 26 0107
Building National Partnerships for the Prevention of Emerging and Reemerging Infectious Diseases is a CDC cooperative agreement (CDC RFA CK 26 0107) run through the National Center for Emerging and Zoonotic Infectious Diseases (NCEZID). The purpose is to create one integrated funding mechanism that strengthens the United States' ability to prevent, detect, and respond to infectious disease threats, especially those that are emerging or coming back in new ways. Rather than focusing on a narrow disease program, the opportunity is framed around building durable national partnerships and practical capacity across clinical care and public health so responses can be faster, more coordinated, and more effective when outbreaks occur or risks escalate.
A key feature of the program is its emphasis on supporting the people and organizations closest to the front lines: clinicians, healthcare professionals, healthcare systems, and institutions involved in patient care, public health practice, and infectious disease control. The CDC is essentially investing in the connective tissue between healthcare delivery and public health action so that when guidance needs to change, when new risks are identified, or when an emergency response is activated, the right stakeholders are already trained, linked, and ready to implement measures quickly. Another stated goal is to capture expert insights from these partners, using their real-world experience to inform and improve public health guidance and practice, which can help ensure recommendations are practical and can be implemented consistently across different healthcare settings.
The activities this funding is meant to support center on building and sustaining core capabilities. That includes strengthening critical infrastructure (systems and processes that help infection prevention function at scale), workforce training (developing and maintaining skills among the healthcare and public health workforce), communication strategies (ensuring timely, clear, and trusted information sharing within and across sectors), and emergency response capacity (so partners can shift rapidly into incident response mode when needed). The overall direction points to long-term readiness: building capabilities that remain in place between emergencies, not just short-term surge activities.
Within that broader structure, the opportunity places special emphasis on expanding national infection prevention capacity through targeted education and training initiatives. Two priority topics explicitly called out are antimicrobial resistance and infection control, reflecting the need to prevent healthcare-associated transmission, improve stewardship and infection prevention practices, and strengthen the ability of healthcare settings to recognize and contain resistant organisms. By prioritizing training and education, the program is designed to improve consistent adoption of evidence-based infection prevention practices across different parts of the country and across varied healthcare environments.
Preparedness and response coordination are also central. The program aims to enhance readiness by supporting surge staffing and by fostering coordination among healthcare and public health partners during emergency response efforts. Surge staffing is important because outbreaks and other infectious disease emergencies often overwhelm routine staffing models, and response effectiveness can hinge on whether trained personnel can be mobilized quickly. Coordination is equally important because infection threats rarely stay within one facility or jurisdiction; the award is structured to encourage organized collaboration so information, resources, and response actions align across hospitals, clinics, public health agencies, and other relevant partners. The mention of faith-based organizations signals that community-connected institutions may play a role in communication, outreach, trust-building, and coordination, depending on the applicant's approach and partnerships.
From an administrative standpoint, this is a discretionary funding opportunity under the Health activity category (CFDA 93.084) using a cooperative agreement instrument, which typically means substantial involvement and collaboration with CDC staff during the period of performance. The opportunity is widely open to many applicant types, including state, county, and local governments; tribal governments and tribal organizations; public and private institutions of higher education; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (including small businesses); public housing authorities; independent school districts; and other unrestricted applicants. The application closing date is listed as 2026-07-01. The award ceiling is up to $30,000,000, and CDC anticipates making about 30 awards, indicating a large national-scale program intended to support multiple partners or networks rather than a single local initiative.Apply for CDC RFA CK 26 0107
- The Centers for Disease Control - NCEZID in the health sector is offering a public funding opportunity titled "Building National Partnerships for the Prevention of Emerging and Reemerging Infectious Diseases" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084.
- This funding opportunity was created on 2026-06-01.
- Applicants must submit their applications by 2026-07-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $30,000,000.00 in funding.
- The number of recipients for this funding is limited to 30 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others, Unrestricted.
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Frequently Asked Questions (FAQs)
What is the "Building National Partnerships for the Prevention of Emerging and Reemerging Infectious Diseases" opportunity?
It is a CDC cooperative agreement funding opportunity (CDC RFA CK 26 0107) administered through the National Center for Emerging and Zoonotic Infectious Diseases (NCEZID). The program is designed to strengthen the United States' ability to prevent, detect, and respond to infectious disease threats, with an emphasis on threats that are emerging or reemerging.
What is the main purpose of this cooperative agreement?
The purpose is to create one integrated funding mechanism that builds durable national partnerships and practical capacity across clinical care and public health. The goal is to enable faster, more coordinated, and more effective responses when outbreaks occur or when infectious disease risks escalate.
Is this opportunity focused on a single disease area or narrow program?
No. The opportunity is framed around strengthening broad, durable capabilities and national partnerships rather than operating as a narrow disease-specific program.
Which CDC center is running this funding opportunity?
The opportunity is run through CDC's National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).
What type of funding mechanism is this?
This is a cooperative agreement. That typically means CDC staff will have substantial involvement and collaboration with recipients during the period of performance.
What does CDC mean by investing in the "connective tissue" between healthcare and public health?
The program emphasizes building and maintaining the relationships, training, and coordination channels between clinicians/healthcare systems and public health partners, so guidance and response actions can be implemented quickly and consistently when circumstances change.
Who is the program intended to support on the front lines?
The opportunity emphasizes supporting clinicians, healthcare professionals, healthcare systems, and institutions involved in patient care, public health practice, and infectious disease control.
How will partner insights be used under this program?
A stated goal is to capture expert insights from funded partners based on real-world experience, and use that input to inform and improve public health guidance and practice so recommendations are more practical and consistently implementable across healthcare settings.
What kinds of activities are intended to be supported by this funding?
The funding is intended to support building and sustaining core capabilities, including critical infrastructure, workforce training, communication strategies, and emergency response capacity, with an overall emphasis on long-term readiness between emergencies.
What is meant by "critical infrastructure" in the context of this opportunity?
It refers to systems and processes that allow infection prevention to function at scale, supporting preparedness and the ability to respond across partners and settings.
What workforce-related activities are emphasized?
The opportunity emphasizes workforce training, specifically developing and maintaining skills among healthcare and public health personnel so they are prepared to implement prevention and response measures effectively.
Why are communication strategies included as a core capability?
The program prioritizes timely, clear, and trusted information sharing within and across sectors. This supports coordinated action across healthcare and public health partners during changing guidance, new risks, or activated emergency responses.
How does the program address emergency response readiness?
It supports emergency response capacity so funded partners can shift rapidly into incident response mode when needed, and it emphasizes readiness that remains in place between emergencies rather than only short-term surge activities.
Is infection prevention training a priority area?
Yes. The opportunity places special emphasis on expanding national infection prevention capacity through targeted education and training initiatives.
Which training topics are explicitly prioritized?
Two priority topics explicitly called out are antimicrobial resistance and infection control.
Why does the opportunity prioritize antimicrobial resistance and infection control?
The description links these priorities to preventing healthcare-associated transmission, improving stewardship and infection prevention practices, and strengthening the ability of healthcare settings to recognize and contain resistant organisms.
How does this opportunity aim to improve consistency across different healthcare settings?
By prioritizing education and training, the program is designed to improve consistent adoption of evidence-based infection prevention practices across different parts of the country and across varied healthcare environments.
What does the opportunity say about preparedness and response coordination?
Preparedness and response coordination are central. The program aims to enhance readiness by supporting surge staffing and fostering coordination among healthcare and public health partners during emergency response efforts.
What is "surge staffing" and why is it highlighted?
Surge staffing refers to the ability to mobilize additional trained personnel quickly during outbreaks or infectious disease emergencies that overwhelm routine staffing models. The program highlights it because response effectiveness may depend on rapid staffing reinforcement.
Why is coordination across organizations and jurisdictions emphasized?
The opportunity notes that infection threats rarely remain within a single facility or jurisdiction. The award encourages organized collaboration so information, resources, and response actions align across hospitals, clinics, public health agencies, and other relevant partners.
Are faith-based organizations relevant to this opportunity?
Yes. The mention of faith-based organizations indicates community-connected institutions may play a role in communication, outreach, trust-building, and coordination, depending on an applicant's approach and partnerships.
What is the CFDA number and activity category for this opportunity?
It is listed under the Health activity category with CFDA 93.084.
Is this a discretionary funding opportunity?
Yes. It is described as a discretionary funding opportunity.
Who is eligible to apply for this cooperative agreement?
The opportunity is widely open to many applicant types, including state, county, and local governments; tribal governments and tribal organizations; public and private institutions of higher education; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (including small businesses); public housing authorities; independent school districts; and other unrestricted applicants.
Does the opportunity allow applications from for-profit organizations?
Yes. For-profit organizations, including small businesses, are included in the listed eligible applicant types.
Are nonprofit organizations required to have 501(c)(3) status to apply?
No. The eligibility list includes nonprofit organizations with or without 501(c)(3) status.
When is the application closing date?
The application closing date is listed as 2026-07-01.
What is the maximum award amount (award ceiling)?
The award ceiling is up to $30,000,000.
How many awards does CDC anticipate making?
CDC anticipates making about 30 awards.
What does the anticipated number of awards suggest about the program's scale?
With an award ceiling up to $30,000,000 and about 30 anticipated awards, the description indicates a large national-scale program intended to support multiple partners or networks rather than a single local initiative.
What is the overall orientation of the program: short-term response or long-term readiness?
The overall direction points to long-term readiness. The opportunity emphasizes building capabilities that remain in place between emergencies, not just short-term surge activities.
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