Cardiovascular Developmental Biology Data Resource Center (U01 - Clinical Trial Not Allowed) | RFA HL 20 017

Opportunity Information: Apply for RFA HL 20 017

The National Institutes of Health (NIH), through the National Heart, Lung, and Blood Institute (NHLBI), offered this funding opportunity to build a Cardiovascular Developmental Biology Data Resource Center as part of the Bench to Bassinet (B2B) Program. It is a discretionary federal grant mechanism using a cooperative agreement (U01), meaning the funded group would carry out the work with substantial scientific and programmatic involvement from NIH staff compared with a standard research grant. The opportunity is explicitly labeled "Clinical Trial Not Allowed," so the work is intended to focus on basic science and data resource development rather than testing interventions in human subjects as a clinical trial.

The central purpose of the Data Resource Center is to speed up discovery in cardiovascular development and congenital heart disease by making it easier for researchers to access, query, and analyze annotated datasets generated from cardiovascular development studies. In practical terms, the award is meant to support an organized, searchable resource that brings together well-described (annotated) research data so investigators can more quickly identify genetic causes (genetic etiology) and understand the biological pathways that drive normal heart development and the origins of congenital heart defects. The emphasis is on facilitating access and enabling powerful queries across data, which typically implies attention to data standardization, harmonization, metadata quality, and user-facing tools that let scientists find and compare information across studies.

This FOA is identified as RFA-HL-20-017 and falls under the health funding activity category, with CFDA number 93.837. The original closing date listed for applications was October 2, 2019, and the opportunity record was created on June 6, 2019. The notice does not provide an award ceiling or the expected number of awards in the text provided, so applicants would normally need to consult the full announcement for budget expectations, project period, milestones, and specific deliverables required under the cooperative agreement.

Eligibility is broad and includes many types of U.S.-based entities: state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other Native American tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status (as long as they are not institutions of higher education under those specific categories); for-profit organizations other than small businesses; and small businesses. The FOA also highlights additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), eligible federal agencies, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions.

Foreign eligibility is more limited. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply as the primary applicant organization. However, non-domestic components of U.S. organizations are eligible, and foreign components (as defined by the NIH Grants Policy Statement) are allowed. In effect, the prime award must be held by an eligible U.S. organization, but parts of the work may be conducted abroad if structured as an allowable foreign component under NIH policy and justified within the project.

Overall, this opportunity is aimed at building shared research infrastructure for the cardiovascular development community: a data resource that organizes and exposes annotated datasets so scientists can more efficiently uncover genetic drivers and biological mechanisms underlying congenital heart disease and related developmental processes. The cooperative agreement structure signals that NIH intended to be actively engaged in shaping the resource to align with B2B program goals and to ensure the resulting data center is broadly useful, accessible, and capable of supporting discovery across multiple cardiovascular development studies.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Cardiovascular Developmental Biology Data Resource Center (U01 - Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.837.
• This funding opportunity was created on 2019-06-06.
• Applicants must submit their applications by 2019-10-02. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA HL 20 017

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