Opportunity Information: Apply for RFA DK 23 003

The National Institutes of Health (NIH) announced this discretionary funding opportunity, RFA-DK-23-003, to establish a single Research Coordinating Center (RCC) for the "Interventions that Address Structural Racism to Reduce Kidney Health Disparities" Consortium. The overarching goal of the Consortium is to support community-engaged intervention research that directly confronts structural racism as a root cause of kidney health disparities. Rather than focusing only on individual behavior or clinical care in isolation, the program is designed to develop, implement, and evaluate interventions that dismantle or reduce the harmful effects of structural racism that shape kidney disease risk, progression, and outcomes in affected communities.

This award uses the U24 cooperative agreement mechanism (clinical trial not allowed), meaning NIH will have substantial involvement in the project and expects the RCC to work in close partnership with NIH staff and the funded Intervention Sites. The RCC is intended to serve as the operational and scientific backbone of the Consortium, coordinating activities across multiple independently funded intervention teams (the Intervention Sites are funded under a related announcement, RFA-DK-22-014). In practical terms, the RCC is responsible for making sure the Consortium functions as a unified program rather than a collection of disconnected projects, with shared processes, aligned milestones, and comparable approaches to measurement and evaluation.

The RCC has three major areas of responsibility. First, it must provide overall organization, management, and administrative support for Consortium activities. That includes planning and running meetings, supporting governance and decision-making structures, facilitating communication across sites, tracking progress toward goals, and ensuring smooth day-to-day operations. Second, it must provide research coordination along with data management and data analysis for Consortium studies. This typically involves developing common data elements where appropriate, harmonizing measures across sites, establishing data workflows and quality controls, maintaining secure data systems, and producing cross-site analyses that help determine whether interventions are effective, scalable, and sustainable across settings. Third, the RCC must foster collaboration and help build a community of investigators with the skills needed to create, test, and spread interventions that address structural drivers of kidney health disparities. This capacity-building emphasis signals that NIH wants the Consortium to strengthen the field by developing shared expertise, encouraging multidisciplinary partnerships, and supporting dissemination of lessons learned so successful approaches can be adopted more broadly.

Eligibility is broad and includes many types of U.S.-based organizations: state, county, city, township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations other than federally recognized governments; public housing authorities and Indian housing authorities; nonprofits with or without 501(c)(3) status; for-profit organizations other than small businesses; and small businesses. The announcement also highlights additional eligible applicant types that are often central to equity-focused and community-engaged work, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. At the same time, the FOA makes clear that foreign entities are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components as defined by the NIH Grants Policy Statement are not allowed.

The opportunity is categorized under the broad activity area of education, food and nutrition, and health, and is associated with CFDA numbers 93.307, 93.361, and 93.847. The original closing date listed for applications was January 12, 2023, and the FOA was created on November 18, 2022. Award ceiling and expected number of awards are not specified in the provided source information, but the structure of the program indicates NIH intended to fund one RCC that would coordinate multiple separately funded Intervention Sites.

  • The National Institutes of Health in the education, food and nutrition, health sector is offering a public funding opportunity titled "Interventions that Address Structural Racism to Reduce Kidney Health Disparities Research Coordinating Center (U24 - Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.307, 93.361, 93.847.
  • This funding opportunity was created on 2022-11-18.
  • Applicants must submit their applications by 2023-01-12. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for RFA DK 23 003

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Frequently Asked Questions (FAQs)

1) What is this funding opportunity?

This is a National Institutes of Health (NIH) discretionary funding opportunity announcement (FOA) identified as RFA-DK-23-003. It supports establishing a single Research Coordinating Center (RCC) for the "Interventions that Address Structural Racism to Reduce Kidney Health Disparities" Consortium.

2) What is the main goal of the Consortium?

The Consortium aims to support community-engaged intervention research that directly confronts structural racism as a root cause of kidney health disparities. The program is intended to develop, implement, and evaluate interventions that dismantle or reduce harmful effects of structural racism that influence kidney disease risk, progression, and outcomes.

3) How is this program different from interventions focused only on individual behavior or clinical care?

Instead of focusing only on individual behaviors or clinical care in isolation, this program emphasizes interventions that address structural drivers (structural racism) that shape kidney health outcomes in affected communities.

4) What is being funded under RFA-DK-23-003?

RFA-DK-23-003 is intended to fund one Research Coordinating Center (RCC) that will serve as the operational and scientific backbone of the Consortium and coordinate activities across multiple independently funded intervention teams.

5) Is NIH planning to fund more than one RCC?

Based on the information provided, NIH intended to fund a single RCC to coordinate the Consortium.

6) What mechanism will be used for this award?

The award uses a U24 cooperative agreement mechanism (clinical trial not allowed). This mechanism indicates substantial NIH involvement in the project.

7) What does "cooperative agreement" mean for this project?

It means NIH will have substantial involvement and expects the RCC to work in close partnership with NIH staff and the funded Intervention Sites to operate the Consortium as a unified program.

8) Are clinical trials allowed under this FOA?

No. The U24 mechanism for this opportunity is specified as "clinical trial not allowed."

9) What are the Intervention Sites and how do they relate to the RCC?

The RCC coordinates multiple independently funded intervention teams known as the Intervention Sites. Those sites are funded under a related announcement, RFA-DK-22-014.

10) What is the RCC expected to do overall?

The RCC is expected to ensure the Consortium functions as a unified program rather than a set of disconnected projects by establishing shared processes, aligned milestones, and comparable approaches to measurement and evaluation across sites.

11) What are the three major areas of responsibility for the RCC?

The RCC has three major responsibility areas: (1) overall organization, management, and administrative support; (2) research coordination including data management and data analysis; and (3) fostering collaboration and capacity-building among investigators working on interventions that address structural drivers of kidney health disparities.

12) What kinds of administrative and management activities are included?

Responsibilities include planning and running meetings, supporting governance and decision-making structures, facilitating communication across sites, tracking progress toward Consortium goals, and ensuring smooth day-to-day operations.

13) What kinds of data-related activities are included?

The RCC is expected to support research coordination and data management/analysis, which may include developing common data elements where appropriate, harmonizing measures across sites, establishing data workflows and quality controls, maintaining secure data systems, and producing cross-site analyses.

14) What is the purpose of cross-site analyses?

Cross-site analyses are intended to help determine whether interventions are effective, scalable, and sustainable across different settings.

15) What does "capacity-building" mean in this context?

Capacity-building refers to fostering collaboration and building a community of investigators with skills needed to create, test, and spread interventions that address structural drivers of kidney health disparities. This includes strengthening shared expertise, encouraging multidisciplinary partnerships, and supporting dissemination of lessons learned so successful approaches can be adopted more broadly.

16) Who is eligible to apply?

Eligibility is broad and includes many U.S.-based entities such as state, county, city, township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations other than federally recognized governments; public housing authorities and Indian housing authorities; nonprofits (with or without 501(c)(3) status); for-profit organizations other than small businesses; and small businesses.

17) Are minority-serving institutions and community-based organizations eligible?

Yes. The FOA highlights additional eligible applicant types including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, and regional organizations.

18) Are U.S. territories eligible to apply?

Yes. The FOA includes U.S. territories or possessions among eligible applicant types.

19) Are federal agencies eligible to apply?

Yes. The FOA lists eligible federal agencies among eligible applicant types.

20) Are foreign organizations eligible to apply?

No. Foreign entities are not eligible to apply.

21) Can a U.S. organization include a non-U.S. component?

No. Non-U.S. components of U.S. organizations are not eligible.

22) Are foreign components allowed under this FOA?

No. Foreign components (as defined by the NIH Grants Policy Statement) are not allowed.

23) What is the activity area associated with this opportunity?

The opportunity is categorized under the broad activity area of education, food and nutrition, and health.

24) What CFDA numbers are associated with this funding opportunity?

The opportunity is associated with CFDA numbers 93.307, 93.361, and 93.847.

25) When was the FOA created?

The FOA was created on November 18, 2022.

26) What was the original application closing date?

The original closing date listed for applications was January 12, 2023.

27) Is the award ceiling provided?

No. Award ceiling information is not specified in the provided source information.

28) Is the expected number of awards provided?

Not explicitly. The provided information indicates NIH intended to fund one RCC to coordinate multiple separately funded Intervention Sites.

29) Why does the RCC matter for the Consortium?

The RCC is designed to make the Consortium function as a coordinated, unified program by aligning processes, milestones, and approaches to measurement and evaluation, while also supporting communication, governance, and cross-site data work.

30) What related funding announcement supports the Intervention Sites?

The Intervention Sites are funded under a related announcement: RFA-DK-22-014.

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