Opportunity Information: Apply for RFA CA 19 002
The NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00) is a National Institutes of Health (NIH) grant opportunity from the National Cancer Institute (NCI) designed to help exceptional graduate students move smoothly from the late stages of their PhD (or equivalent doctoral training) into a strong, cancer-focused postdoctoral position and then onward toward an independent research career. The central goal is to encourage and retain trainees who have already been identified by their institutions as having outstanding potential and a clear interest in becoming independent cancer researchers. In practical terms, the program is structured to support both the final phase of predoctoral training and the early postdoctoral period, while also emphasizing career development activities that build the skills, experiences, and professional trajectory needed for long-term success in cancer research.
This opportunity is listed as a discretionary grant under the funding activity category of education and health, with CFDA number 93.398, and it was released under Funding Opportunity Number RFA-CA-19-002. The original closing date shown for the competition is February 22, 2019, and the record notes no stated award ceiling and no specified number of expected awards in the provided source text. The opportunity was created on September 17, 2018. While the summary highlights the intent and broad structure of the F99/K00 mechanism, the full funding opportunity announcement is where applicants would find the specific budget rules, duration, allowable costs, review criteria, and the detailed requirements for transitioning from the F99 phase (predoctoral) to the K00 phase (postdoctoral career development).
Eligibility in the source data is broad across many types of U.S.-based organizations and public entities. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities/Indian housing authorities; and Native American tribal organizations other than federally recognized tribal governments. The eligibility list also includes nonprofits both with and without 501(c)(3) status (as long as they are not institutions of higher education in those nonprofit categories), for-profit organizations other than small businesses, small businesses, and an “other” category that can apply depending on how NIH defines eligibility in the announcement.
The opportunity also explicitly names several categories of institutions and organizations as “other eligible applicants,” underscoring NCI’s interest in supporting a wide range of research and training environments. These include Alaska Native and Native Hawaiian Serving Institutions; Asian American, Native American, and Pacific Islander Serving Institutions (AANAPISIs); faith-based or community-based organizations; Hispanic-serving institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); regional organizations; eligible federal agencies; and U.S. territories or possessions. These categories are important because they signal that the program is open to a diverse set of institutional contexts and may help broaden participation across different communities and geographic regions, while still focusing on the core mission of developing future independent cancer researchers.
At the same time, the announcement places clear limits on foreign involvement. Non-domestic (non-U.S.) entities (foreign organizations) and non-domestic (non-U.S.) entities (foreign institutions) are explicitly stated as not eligible to apply. In addition, non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as defined by the NIH Grants Policy Statement) are not allowed. This means the award is intended to be carried out fully within eligible domestic organizational structures, without foreign component arrangements that NIH would classify as foreign participation under its policy definitions. For anyone considering applying, these restrictions make it especially important to review the NIH Grants Policy Statement definitions and the specific FOA language so there is no ambiguity about whether a proposed training or research plan would be considered to involve a foreign component.
Overall, the F99/K00 is aimed at strengthening the cancer research pipeline by identifying high-potential graduate students and providing a structured, supported transition into postdoctoral training, paired with purposeful career development toward independence. It is fundamentally a workforce and career-development investment by NCI, focused on helping promising trainees position themselves for long-term impact as independent investigators in cancer research, while keeping eligibility centered on U.S.-based institutions and disallowing foreign components.Apply for RFA CA 19 002
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "The NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.398.
- This funding opportunity was created on 2018-09-17.
- Applicants must submit their applications by 2019-02-22. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00)
What is the NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00)?
The NCI Predoctoral to Postdoctoral Fellow Transition Award (F99/K00) is an NIH grant opportunity from the National Cancer Institute (NCI) designed to help exceptional graduate students transition from the late stages of PhD (or equivalent doctoral) training into a strong, cancer-focused postdoctoral position and then progress toward an independent research career.
What is the main purpose of the F99/K00 program?
The central goal is to encourage and retain trainees who have already been identified by their institutions as having outstanding potential and a clear interest in becoming independent cancer researchers. The program supports both training and career development to strengthen the cancer research pipeline.
How is the F99/K00 award structured?
The mechanism is structured to support two stages: (1) the final phase of predoctoral training (the F99 phase) and (2) the early postdoctoral period focused on career development (the K00 phase). It also emphasizes career development activities aimed at building skills and experiences needed for long-term success in cancer research.
Who is the target trainee audience for this opportunity?
The opportunity targets exceptional graduate students in the late stages of their PhD (or equivalent doctoral training) who are interested in cancer research and who are aiming for an independent research career.
What research area is emphasized by this transition award?
The program is cancer-focused and is intended to develop future independent investigators in cancer research.
Which agency and institute sponsor this grant opportunity?
This is an NIH grant opportunity sponsored by the National Cancer Institute (NCI).
What is the Funding Opportunity Number (FOA) for this award?
The Funding Opportunity Number listed is RFA-CA-19-002.
What is the CFDA number associated with this opportunity?
The CFDA number provided is 93.398.
What funding activity category is this opportunity listed under?
It is listed as a discretionary grant under the funding activity category of education and health.
When was this opportunity created and what was the original closing date shown?
The record indicates the opportunity was created on September 17, 2018, and the original closing date shown for the competition is February 22, 2019.
Is there a stated award ceiling or a specified number of expected awards?
No. The provided source text notes no stated award ceiling and no specified number of expected awards.
Where are the detailed requirements (budget rules, duration, allowable costs, review criteria) described?
The summary notes that the full funding opportunity announcement is where applicants would find the specific budget rules, duration, allowable costs, review criteria, and detailed requirements for transitioning from the F99 (predoctoral) phase to the K00 (postdoctoral career development) phase.
What types of U.S.-based organizations are listed as eligible applicants?
The eligibility list in the source data includes many types of U.S.-based organizations and public entities, including:
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Federally recognized Native American tribal governments
- Public housing authorities / Indian housing authorities
- Native American tribal organizations other than federally recognized tribal governments
- Nonprofits with 501(c)(3) status (other than institutions of higher education in those nonprofit categories)
- Nonprofits without 501(c)(3) status (other than institutions of higher education in those nonprofit categories)
- For-profit organizations other than small businesses
- Small businesses
- Other (as defined by NIH in the announcement)
What additional categories are explicitly called out as "other eligible applicants"?
The opportunity explicitly names additional categories, including:
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American, Native American, and Pacific Islander Serving Institutions (AANAPISIs)
- Faith-based or community-based organizations
- Hispanic-serving institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Regional organizations
- Eligible federal agencies
- U.S. territories or possessions
Are foreign (non-U.S.) organizations or institutions eligible to apply?
No. Non-domestic (non-U.S.) entities (foreign organizations) and non-domestic (non-U.S.) entities (foreign institutions) are explicitly stated as not eligible to apply.
Are non-domestic components of U.S. organizations eligible?
No. Non-domestic components of U.S. organizations are stated as not eligible to apply.
Are foreign components allowed under this opportunity?
No. Foreign components (as defined by the NIH Grants Policy Statement) are not allowed.
What is meant by a "foreign component" in this context?
The information provided indicates that foreign components are defined by the NIH Grants Policy Statement and are not allowed for this opportunity. Applicants are advised (in the summary) to review NIH policy definitions and the FOA language to avoid ambiguity about whether a proposed plan would involve a foreign component.
Why do the eligibility categories emphasize different institution types (like HBCUs, HSIs, and TCCUs)?
The named categories signal that the program is open to a diverse set of institutional contexts and may help broaden participation across different communities and geographic regions, while maintaining the core mission of developing future independent cancer researchers.
What career stage transitions does this award aim to support?
It aims to support the transition from late-stage doctoral training to a cancer-focused postdoctoral position, and then onward toward an independent research career.
Does the summary include the exact budget amount, project length, or specific allowable costs?
No. The summary indicates that those specifics (budget rules, duration, allowable costs, review criteria) are found in the full funding opportunity announcement rather than in the provided source text.
What should applicants pay special attention to when planning their training or research activities?
Based on the information provided, applicants should pay special attention to the restrictions on foreign involvement (including foreign components) and should consult the NIH Grants Policy Statement definitions and the FOA language to ensure the plan is fully compliant.
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